According to Persistence Market Research, the global lentiviral expression systems market will witness an exponentiation between 2020 and 2030.
Lentiviral expression systems come across as proprietary combination on the part of plasmids to collectively express viral proteins essential to assemble vector into the infectious virions. Of late, the lentiviral packaging systems have segregated viral components into 3-4 plasmids for preventing unwanted infection. They come across as one of the sub-classes of retroviruses that could be used for stable as well as transient gene expression. They are capable of infecting both – non-proliferating and proliferating cells. It has been observed that lentiviral vectors do deliver genes to macrophages, lymphocytes, and neurons.
Lentiviral expression systems, on the basis of expression system components, spans lentiviral promoter (lentivirus promoter vectors, lentiviral fusion tags, lentivirus promoterless vectors, and various other accessories. The application sector includes functional assays, recombinant protein expression, in vitro transcription, protein characterization, and the ones meant for research.
The end-users comprise biotechnological companies, research/academic institutes, CROs (contract research organizations), and pharmaceutical companies.
North America dominates the lentiviral expression systems market. This could be credited to the growing emphasis on protein production and expression and funding from the government for extensive research in this regard. Also, application areas like functional genomics, protein purification & expression, protein structural analysis, determination of protein-protein interactions are expected to upscale the European market in the years to come. Increase in healthcare expenditures in the Asia-Pacific is expected to put at the third position in the forecast period.
The key market participants include Cell Biolabs, Merck KGaA, Dharmacon, Takara Bio, ABM Industries, Cell Biolabs, ATUM, Fujifilm Diosynth Biotechnologies, ThermoFisher Scientific, GeneCopoeia, and System Biosciences. ThermoFisher’s Invitrogen ViraPower Lentiviral Expression System, as the name suggests, does facilitate creating HIV-1-based, replication-incompetent lentivirus used for delivering and expressing the gene (s) of interest in non-dividing/dividing mammalian cells. Likewise, the players are catering to the needs of patients. The future scenario is expected to be the same.
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