Description:

Dystrophic Epidermolysis Bullosa Treatment Market: Introduction

According to the report, the global dystrophic epidermolysis bullosa treatment market was valued over US$ 412 Mn in 2019 and is projected to expand at a CAGR of ~5% from 2020 to 2030. Dystrophic epidermolysis bullosa (DEB) is the second most common form of epidermolysis bullosa. The prevalence of DEB varies from 1 per 49,000 inhabitants in Scotland to 1 per 420,168 in the U.S. According to the U.S. National Library of Medicine, the prevalence of recessive and dominant dystrophic epidermolysis bullosa is estimated at 3.3 per million people. 

North America dominated the global dystrophic epidermolysis bullosa treatment market in 2019 and the trend is anticipated to continue during the forecast period. The rise in population suffering from various diseases in North America has increased the number of patients visiting hospitals. Hence, the consumption of dystrophic epidermolysis bullosa treatment products is expected to increase during the forecast period. 

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North America’s large share of the global dystrophic epidermolysis bullosa treatment market can be attributed to high cost of biologic drugs compared to other regions. It is a key target region for all players in the global dystrophic epidermolysis bullosa treatment market. Asia Pacific is likely to be a highly lucrative market for dystrophic epidermolysis bullosa treatment from 2020 to 2030. The market in the region is projected to expand at a high CAGR during the forecast period.

Antibiotics to Dominate Global Market

In terms of treatment type, the global dystrophic epidermolysis bullosa treatment market has been classified into antibiotics, corticosteroids, opioid analgesics, anticonvulsant, and others. The antibiotics segment dominated the global dystrophic epidermolysis bullosa treatment market in 2019 and the trend is projected to continue during the forecast period. 

A large number of antibiotics is in late phases of clinical pipeline trials and are likely to be commercialized between 2019 and 2025. Anticipated launch and adoption of antibiotics to address unmet medical needs in dystrophic epidermolysis bullosa treatment are expected to propel the segment during the forecast period.

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Dominant Dystrophic Epidermolysis Bullosa (DDEB) to be Highly Lucrative

Based on service provider, the global dystrophic epidermolysis bullosa treatment market has been bifurcated into dominant dystrophic epidermolysis bullosa (DDEB) and recessive dystrophic epidermolysis bullosa (RDEB). The dominant dystrophic epidermolysis bullosa (DDEB) segment dominated the global dystrophic epidermolysis bullosa treatment market due to large number of patients suffering from dominant dystrophic epidermolysis bullosa. According to the National EB Registry, the overall prevalence of EB is 11.07 per one million live births. The prevalence of DDEB and RDEB is 1.49 and 1.35 per one million live births, respectively.

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Competition Landscape

Key players in the global dystrophic epidermolysis bullosa treatment market include Krystal Biotech, Castle Creek Biosciences, Inc., Abeona Therapeutics, Inc., Amryt Pharma plc, Wings Therapeutics, Phoenix Tissue Repair, InMed Pharmaceuticals, Inc., RegeneRx, and Holostem Terapie Avanzate S.r.l.

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